How CBD works in the human body

How CBD works in the human body



Some people are skeptical of CBD because they believe that cannabinoid-infused products are just a flash in the pan, a gimmick trend that is unlikely to produce meaningful results.Others insist on long-term holding Myths and misunderstandings Regarding CBD, the stigma associated with cannabis use persists.

If you are interested in some of the many possible benefits of CBD use, but are still hesitant, you may find it helpful to explore the topic from a different perspective. Let’s take a look at what CBD is, what it is not, and how CBD works in the human body.

What is CBD derived from hemp?

CBD is a commonly used abbreviation for cannabidiol and is one of more than 100 plant elements classified as cannabinoids. Since cannabinoids are the highest in cannabis, there are two potential sources of CBD, hemp and hemp.

Cannabis plants produce varying amounts of CBD and high levels of THC (tetrahydrocannabinol), a cannabinoid known for producing the type of cannabis poisoning. Although hemp is also a cannabis plant, the whole plant extract contains only trace amounts of THC, 0.3% or less. This is why most people interested in the health potential of CBD choose products from the stems, stems and flowers of the industrial hemp plant.

How does CBD work? What effect does it have on the human body?

Marijuana has always been used for medicinal purposes Recorded history. Although an American chemist isolated cannabidiol (CBD) in the 1940s, researchers can only speculate on how (and why) cannabinoids help so many seemingly unrelated health problems. This situation changed in the early 1990s, when researchers discovered a previously undiscovered regulatory system that is responsible for almost all the key functions in the body, the endocannabinoid system. 1

Today, we know that CBD and other cannabinoids work by interacting with ECS receptors and several other molecular targets throughout the body. Although research on ECS functions is still in its infancy, we do know that there are three main components. 2

Endocannabinoid System Receptor

In your entire body, there are two types of endocannabinoid system receptors. Your CB1 receptors are highly concentrated in your brain and spine. These are receptors involved in regulating energy levels, metabolism, emotional response and memory recall. Your CB2 receptors are highly concentrated in your peripheral nervous system and overall immune system.

Endocannabinoid system messenger

In the early 1990s, researchers identified two lipids that interact with CB1 and CB2 receptors in your body as needed, namely arachidonic acid (AEA) and 2-arachidonic glycerol (2-AG). Anandamide helps to regulate emotions, stress responses, and the perception of happiness and pain. Cannabinoid 2-AG is believed to play an important role in immune system function and appetite regulation. 3

Metabolic Enzymes

Your endocannabinoid system also relies on the production of metabolic enzymes, which helps to ensure that your ECS messenger is long enough to perform its intended function. Once their message is transmitted, anandamide is broken down by amide hydrolase (FAAH). 2-Ag is broken down by two metabolic enzymes FAAH and MAGL (monoacylglycerol lipase)4.

What is the purpose of the ECS function?

According to the research so far, the main purpose of ECS function is to regulate the process of homeostasis, that is, the internal equilibrium state on which all organisms depend for survival. When internal or external influences threaten this balance, steady state explains the system’s response that helps rebuild acceptable parameters. 5

Although there are still many things to learn, we know that ECS signals are responsible for almost every key function of the human body, from memory, learning and stress response, to sleep cycle regulation, cardiovascular function and reproductive processes. It is now clear that the ECS function helps keep the basic processes running properly, and some of today’s most respected cannabis researchers suspect that ECS defects can cause disease. 6

How does CBD affect ECS functions?

CBD is pleiotropic, which means that cannabinoids interact with multiple pathways to produce many possible effects, including receptors for the endocannabinoid system. But unlike THC, which directly binds to CB1 and CB2 receptors, CBD has an indirect effect. Although we still don’t understand the effect of CBD on ECS function, research on the therapeutic potential of cannabinoids has shown that cannabinoids have considerable analgesic, anti-inflammatory, antispasmodic and neuroprotective properties, which can be combined with more than 65 molecular targets. To explain the interaction of points. 7,8

Although most of the evidence supporting CBD use is based on laboratory results, a relatively small number of clinical trials, and the testimony of many satisfied CBD users, it is undeniable that hemp-derived CBD has some very significant health potential. The impact of CBD’s support of ECS functions seems to depend on which key processes can be restored to equilibrium (steady state) with ECS support.

Why do people use CBDistillery® CBD products?

Have many reasons Consider adding CBDistillery® tinctures, capsules, gummies or topical agents to your daily life. Based on feedback from nearly 2,000 CBD users, most people start to use our hemp-derived CBD products to improve sleep, relax, or relieve stiffness, pain or inflammation after physical activity.

An impressive 88% of survey respondents also told us that our cannabis-derived products seem to help relieve mild or temporary anxiety. Although the only way to understand how you personally benefit from any cannabis-derived cannabinoid is to choose a product and try it, the following observations seem to support the experience of our 2019 survey respondents.

Possible benefits of discomfort

If you are seeking help for discomfort after physical activity like our survey, you may find that experts in the field tend to attribute the pain-relieving potential of CBD to its effects on anandamide and ECS receptors that regulate inflammation. This bit of information may explain why 90% of survey respondents prefer CBD to turmeric, which is a natural supplement that athletes often like to use for post-workout recovery. 9,10

Potential to relieve inflammation

Inflammation is a natural response to injury, disease, and stress. Chronic inflammation is usually related to lack of sleep and immune system dysfunction. The type of inflammation that causes stiffness, swelling, and pain after physical activity is usually caused by the immune system response necessary to help overworked joints and muscles recover.According to research so far, CBD has shown considerable Anti-inflammatory (medicine characteristic.

Potential to improve sleep

Although there are many potential causes of poor sleep, many sleep experts attribute the most common types of sleep difficulties to stress and anxiety, including difficulty falling asleep and frequent waking up. Based on the CBD research results published in 2019, the current survey seems to confirm what CBD users have been telling us for years. In a small study involving 72 subjects, nearly 80% of study participants reported reduced anxiety, and nearly 70% reported better sleep. 11

Possible benefits of stress relief

Stress and anxiety are not the same, but they cause similar physical and emotional reactions. The longer your system is on high alert, the longer your body may need to recover. Although more research is needed, a Brazilian study investigating the impact of CBD on public speaking-related stress has shown promising results. Compared with the control group, participants who received CBD reported fewer stress-related symptoms. Researchers have noticed similar results in studies exploring the possible effects of CBD on anxiety. 9

Are you ready to experience the many possible benefits of CBD?

Knowing that CBD works by interacting with numerous receptors (over 65 molecular targets) throughout the body, it is easier to understand how individual plant elements display such amazing health and wellness potential. Based on feedback from our survey participants, most people reported that they have achieved good results after 7-14 days of continuous use.

If you want to learn more about some of the possible benefits of supporting ECS ??functions through CBD, please visit CBDistillery® go download The Ultimate CBD User GuideThen consider browsing our selection of hemp-derived CBD, CBG and CBN products. All CBDistillery® products are derived from non-GMO, naturally cultivated crops, Third-party testing, American Hemp Authority™ certification, cruelty-free, and backed by our 60-day satisfaction guarantee.

other sources:

1. CBD project. (2021) What is CBD?

2. Health hotline. C Repol. (May 17, 2019) A simple guide to the endocannabinoid system.

3. Solar energy. M Haslam. (April 6, 2020) Introducing Anandamide and 2-AG.

4. Protein and peptide letters. B Basavarajappa (2007) involves key enzymes in the metabolism of endocannabinoids.

5. Journal of Young Researchers. C Saraberry, L Astern. (June 1, 2018) The endocannabinoid system, our universal regulator.

6. Cannabis and cannabinoid research. E Russell. (2016) Reconsidering clinical endocannabinoid deficiency: current research supports theories of migraine, fibromyalgia, irritable bowel, and other refractory syndromes.

7. Physiology. Lingresti et al. (September 14, 2016) From phytocannabinoids to cannabinoid receptors and endocannabinoids: the multiple physiological and pathological effects of complex pharmacology.

8. Frontiers of Pharmacology. G Gonzalez-Cuevas et al. (October 18, 2021) Editorial: Cannabidiol treatment in neurotherapeutic intervention.

9. Health hotline. J Kubala. (November 26, 2021) 6 health benefits of CBD oil-and side effects?

10. Easy to find. M Radlov. (May 4, 2019) Here is how turmeric promotes athletes’ recovery.

11. Health hotline. S. Ferguson. (May 11, 2020) CBD for insomnia. Benefits, side effects and treatment.


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