Global Equols Market Size and Market Scenario 2022 by
Equols market has been segmented into various major regions including North America, Europe, Asia Pacific, South America, Middle East and Africa.
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Equols Market Analysis and Insights:
Equol, a soybean metabolite, is an important isoflavone in humans, specifically binds to 5?-DHT and has low affinity for the recombinant estrogen receptor ER?. Equol is a metabolite produced from the soy phytoestrogen daidzein through the action of the gut flora. Equol has a higher affinity for both ERs (estrogen receptors including ERalpha and ERbeta). Equol exists as the enantiomers R-Equol and S-Equol. S-equol has high binding affinity, preferentially for ERbeta with a Ki of 16 nM, while R-equol binds weaker and with a preference for ERalpha K with a Ki of 50 nM. Equol is superior to all other isoflavones in its antioxidant effect. Equol has anti-estrogenic properties. Equol is 100 times more potent than daidzein at stimulating an estrogenic response. Equol is also more effective than daidzein in competing with 3 H-estradiol for binding to the ER. Equol stimulates the growth of MCF-7 cells in a concentration-dependent manner. Although equol has estrogenic activity, co-exposure of MCF-7 cells with equol and estradiol is effective in reducing…